Hydrochloric Acid → 4-(4-Amino-phenyl)-piperidine-1-carboxylic Acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

HRID 1570677Notes

Reaction equation

HRID 1570677 reaction equation
[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10]1.[ClH:35].[NH2:22][c:23]1[cH:24][cH:25][c:26]([CH:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:27][cH:28]1>>[C:2](=[O:3])([O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10]1)[N:32]1[CH2:31][CH2:30][CH:29]([c:26]2[cH:25][cH:24][c:23]([NH2:22])[cH:28][cH:27]2)[CH2:34][CH2:33]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 220477624-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformateHCID 220478414-(Piperidin-4-yl)aniline

Product 1

HCID 695196604-(4-Amino-phenyl)-piperidine-1-carboxylic Acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

Sources & evidence

ORD record
ord-ea6da47fa01f4177a632d5ae08c046d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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