Hydrochloric Acid → N-Methoxy-2-chloro-5-(4-chloro-5-difluoromethoxy-1-methyl-1H-pyrazol-3-yl)-4-fluorobenzamide

HRID 1570744Notes

Reaction equation

HRID 1570744 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:30][O:31][NH2:32].[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[cH:7][c:8](-[c:12]2[n:13][n:14]([CH3:22])[c:15]([O:18][CH:19]([F:20])[F:21])[c:16]2[Cl:17])[c:9]([F:11])[cH:10]1.[ClH:29].[K+:27].[K+:28].[OH2:40]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:32][O:31][CH3:30])[cH:7][c:8](-[c:12]2[n:13][n:14]([CH3:22])[c:15]([O:18][CH:19]([F:20])[F:21])[c:16]2[Cl:17])[c:9]([F:11])[cH:10]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 1140TolueneHCID 4113O-MethylhydroxylamineHCID 19660Carbonate IonHCID 212540122-Chloro-5-(4-chloro-5-difluoromethoxy-1-methyl-1H-pyrazol-3-yl)-4-fluorobenzoyl chloride

Product 1

HCID 21254033N-Methoxy-2-chloro-5-(4-chloro-5-difluoromethoxy-1-methyl-1H-pyrazol-3-yl)-4-fluorobenzamide

Sources & evidence

ORD record
ord-ecbd12f9ede242c780f3ab4c4151cabd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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