Pyridine → tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

HRID 1571007Notes

Reaction equation

HRID 1571007 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH:9]([CH2:10][OH:11])[CH2:12][CH2:13][CH2:14]1.[S:15](=[O:16])(=[O:17])([c:18]1[cH:19][cH:20][c:21]([CH3:22])[cH:23][cH:24]1)[Cl:25].[cH:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH:9]([CH2:10][O:11][S:15](=[O:16])(=[O:17])[c:18]2[cH:19][cH:20][c:21]([CH3:22])[cH:23][cH:24]2)[CH2:12][CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 13110388tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-83411cc4ead346818be086b12b04a7f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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