Tetrahydrofuran → Methyl 2-[5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-cyclopropyl-2-hydroxyethyl)-3-methyl-2-oxopiperidin-3-yl]acetate
Reaction equation
[C:1]([Si:2]([c:3]1[cH:4][cH:5][cH:39][cH:40][cH:41]1)([O:6][CH2:7][CH:8]([CH:9]1[CH2:10][CH2:11]1)[N:12]1[C:13](=[O:38])[C:14]([CH3:32])([CH2:33][C:34](=[O:35])[O:36][CH3:37])[CH2:15][CH:16]([c:25]2[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]2)[CH:17]1[c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1)[c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)([CH3:48])([CH3:49])[CH3:50].[CH2:52]([N+:53]([CH2:54][CH2:55][CH2:56][CH3:57])([CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH2:64][CH3:65])[CH2:66][CH2:67][CH3:68].[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[F-:51]>>[OH:6][CH2:7][CH:8]([CH:9]1[CH2:10][CH2:11]1)[N:12]1[C:13](=[O:38])[C:14]([CH3:32])([CH2:33][C:34](=[O:35])[O:36][CH3:37])[CH2:15][CH:16]([c:25]2[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]2)[CH:17]1[c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f1b918c4abaf4351b2f49b5e791b047e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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