Dichloromethane → 3-[3-(1-cyclohexylcarbonylmethyl-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl)ureido]benzoic acid
Reaction equation
[CH2:52]([Cl:53])[Cl:54].[CH:8]1([C:14](=[O:15])[CH2:16][N:17]2[C:18](=[O:51])[CH:19]([NH:34][C:35](=[O:36])[NH:37][c:38]3[cH:39][c:40]([C:44](=[O:45])[O:46][C:47]([CH3:48])([CH3:49])[CH3:50])[cH:41][cH:42][cH:43]3)[CH2:20][N:21]([CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[c:22]3[c:23]2[cH:24][cH:25][cH:26][cH:27]3)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH:8]1([C:14](=[O:15])[CH2:16][N:17]2[C:18](=[O:51])[CH:19]([NH:34][C:35](=[O:36])[NH:37][c:38]3[cH:39][c:40]([C:44](=[O:45])[OH:46])[cH:41][cH:42][cH:43]3)[CH2:20][N:21]([CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[c:22]3[c:23]2[cH:24][cH:25][cH:26][cH:27]3)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a79aabae24d84f5f8132178af5c572be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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