N-methyl-2-pyrrolidone → Methyl 3-[4-(3-chloro-4-methoxybenzylamino)-5,6,7,8-tetrahydro-[1]-benzothieno[2,3-d]pyrimidin-2-yl]propionate

HRID 1571450Notes

Reaction equation

HRID 1571450 reaction equation
[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([CH2:8][CH2:9][C:10](=[O:11])[O:12][CH3:13])[n:7]1)[s:14][c:15]1[c:16]2[CH2:17][CH2:18][CH2:19][CH2:20]1.[Cl:21][c:22]1[cH:23][c:24]([CH2:25][NH2:26])[cH:27][cH:28][c:29]1[O:30][CH3:31]>>[c:2]1([NH:26][CH2:25][c:24]2[cH:23][c:22]([Cl:21])[c:29]([O:30][CH3:31])[cH:28][cH:27]2)[c:3]2[c:4]([n:5][c:6]([CH2:8][CH2:9][C:10](=[O:11])[O:12][CH3:13])[n:7]1)[s:14][c:15]1[c:16]2[CH2:17][CH2:18][CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 7380383-Chloro-4-methoxybenzylamineHCID 11001423Methyl 3-(4-chloro-5,6,7,8-tetrahydro-[1]benzothieno[2,3-d]pyrimidin-2-yl)propionate

Product 1

HCID 10873971Methyl 3-[4-(3-chloro-4-methoxybenzylamino)-5,6,7,8-tetrahydro-[1]-benzothieno[2,3-d]pyrimidin-2-yl]propionate

Sources & evidence

ORD record
ord-e737034f7a1b4c1582ea4888b6b73abf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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