Pyridine → 1-(2,4-difluorophenyl)-1-(4-(4-cyanothiazol-2-yl)-thiophen-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethanol
Reaction equation
[F:1][c:2]1[c:3]([C:9]([CH2:10][n:11]2[n:12][cH:13][n:14][cH:15]2)([OH:16])[c:17]2[s:18][cH:19][c:20](-[c:22]3[s:23][cH:24][c:25]([C:27]([NH2:28])=[O:29])[n:26]3)[cH:21]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[P:30]([Cl:31])([Cl:32])([Cl:33])=[O:34].[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[F:1][c:2]1[c:3]([C:9]([CH2:10][n:11]2[n:12][cH:13][n:14][cH:15]2)([OH:16])[c:17]2[s:18][cH:19][c:20](-[c:22]3[s:23][cH:24][c:25]([C:27]#[N:28])[n:26]3)[cH:21]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-19e292772d654aa0b8fc852c6a62af58
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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