Ethanolamine → Linaprazan

HRID 1572049Notes

Reaction equation

HRID 1572049 reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][c:10]([C:12](=[O:13])[O:14][CH:15]([CH3:16])[CH3:17])[cH:11]2)[c:18]([CH3:22])[c:19]([CH3:21])[n:20]3)[c:23]([CH3:27])[cH:24][cH:25][cH:26]1.[NH2:28][CH2:29][CH2:30][OH:31]>>[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][c:10]([C:12](=[O:13])[NH:28][CH2:29][CH2:30][OH:31])[cH:11]2)[c:18]([CH3:22])[c:19]([CH3:21])[n:20]3)[c:23]([CH3:27])[cH:24][cH:25][cH:26]1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 8028TetrahydrofuranHCID 11164436Isopropyl 8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylate

Product 1

HCID 9951066Linaprazan

Sources & evidence

ORD record
ord-33eef598cfe045b0a8d73c2a3f76e8e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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