Methyl iodide → 6-(2,6-Diethyl-phenyl)-2-ethyl-4-methoxy-nicotinic acid methyl ester
Reaction equation
[CH3:2][CH:3]([N-:4][CH:5]([CH3:6])[CH3:7])[CH3:8].[CH3:32][I:33].[CH3:9][O:10][C:11]([c:12]1[c:13]([CH3:30])[n:14][c:15](-[c:20]2[c:21]([CH2:28][CH3:29])[cH:22][cH:23][cH:24][c:25]2[CH2:26][CH3:27])[cH:16][c:17]1[O:18][CH3:19])=[O:31].[Li+:1]>>[CH3:2][CH2:30][c:13]1[c:12]([C:11]([O:10][CH3:9])=[O:31])[c:17]([O:18][CH3:19])[cH:16][c:15](-[c:20]2[c:21]([CH2:28][CH3:29])[cH:22][cH:23][cH:24][c:25]2[CH2:26][CH3:27])[n:14]1Participants
5
Sources & evidence
- ORD record
- ord-dfbfda57995249a38763c5ac8f7b95c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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