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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1572155Generated: November 2, 2026

Methyl iodide → 2-anilino-7-chloro-6-fluoro-5-methyl-1-phenyl-1,8-naphthyridin-4(1H)-one

https://huagongshe.com/reaction/1572155

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
Reactant1,2,2,3-TetramethylpiperidineHCID 18761772—
Reactant2-anilino-7-chloro-6-fluoro-1-phenyl-1,8-naphthyridin-4(1H)-oneHCID 21948186—
ReactantButyllithiumHCID 178418339—
Product2-anilino-7-chloro-6-fluoro-5-methyl-1-phenyl-1,8-naphthyridin-4(1H)-oneHCID 21948206—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-0a7486edfa0a4c2fbfcbeb83a8b96a3b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)