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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157230Generated: November 2, 2026

1,2-Dichloroethane → 4-chloro-7-(methyloxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazoline

https://huagongshe.com/reaction/157230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantDiisopropylethylamineHCID 81531—
Reactant7-methoxy-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4(3H)-oneHCID 135510696—
Product4-chloro-7-(methyloxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolineHCID 85912883—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b5f0deed04c94fa7b66389eb8cda70a3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)