1,2-Dichloroethane → 4-chloro-7-(methyloxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazoline
Reaction equation
[CH2:35]([Cl:36])[CH2:37][Cl:38].[CH3:1][O:2][c:3]1[cH:4][c:5]([O:14][CH:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[c:6]2[c:7](=[O:13])[nH:8][cH:9][n:10][c:11]2[cH:12]1.[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([O:14][CH:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[c:6]2[c:7]([Cl:23])[n:8][cH:9][n:10][c:11]2[cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-b5f0deed04c94fa7b66389eb8cda70a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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