Phosphorus oxychloride → 1-Chloro-4-hydroxy-7-iodo-isoquinoline-3-carboxylic acid butyl ester
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[nH:9][c:10](=[O:20])[c:11]2[cH:12][c:13]([I:19])[cH:14][cH:15][c:16]2[c:17]1[OH:18].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][c:10]([Cl:23])[c:11]2[cH:12][c:13]([I:19])[cH:14][cH:15][c:16]2[c:17]1[OH:18]Participants
3
Sources & evidence
- ORD record
- ord-baee3461cf194109a4e63792ad92bab8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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