Dichloromethane → N-(2-cyanoethyl)-4-aminopiperidine

HRID 1572626Notes

Reaction equation

HRID 1572626 reaction equation
[C:8](#[N:9])[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:16][CH2:17]1.[Cl:26][CH2:27][Cl:28].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[C:8](#[N:9])[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([NH2:18])[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59862765tert-Butyl 1-(2-cyanoethyl)piperidin-4-ylcarbamate

Product 1

HCID 22562162N-(2-cyanoethyl)-4-aminopiperidine

Sources & evidence

ORD record
ord-d0d15cba97e94442a673727d2d82e599
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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