3-Chlorobenzoic Acid → 3-Chloro-3'-methoxybenzophenone

HRID 1572789Notes

Reaction equation

HRID 1572789 reaction equation
[Br:6][c:7]1[cH:8][c:9]([O:13][CH3:14])[cH:10][cH:11][cH:12]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Cl:15][c:16]1[cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24]1>>[c:7]1([C:19]([c:18]2[cH:17][c:16]([Cl:15])[cH:24][cH:23][cH:22]2)=[O:20])[cH:8][c:9]([O:13][CH3:14])[cH:10][cH:11][cH:12]1

Participants

5

Reactant 4

HCID 4473-Chlorobenzoic AcidHCID 8028TetrahydrofuranHCID 169713-BromoanisoleHCID 178418339Butyllithium

Product 1

HCID 27576323-Chloro-3'-methoxybenzophenone

Sources & evidence

ORD record
ord-98ab98d9420947ff9224690ebcfd4d30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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