Dimethylformamide → 4-Chloro-2-[4-(1,1-dimethylethyl)phenyl]quinazoline

HRID 1572839Notes

Reaction equation

HRID 1572839 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[n:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]3[c:19](=[O:21])[nH:20]2)[cH:9][cH:10]1.[CH2:31]1[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]1.[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[S:22]([Cl:23])([Cl:24])=[O:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[n:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]3[c:19]([Cl:24])[n:20]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8078CyclohexaneHCID 24386Thionyl ChlorideHCID 135443955ST50050588

Product 1

HCID 7320204-Chloro-2-[4-(1,1-dimethylethyl)phenyl]quinazoline

Sources & evidence

ORD record
ord-db8828b1f042447792b9445177592e4d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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