Tetrahydrofuran → 5-Acetyl4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyridine-3-carboxylic acid

HRID 1572878Notes

Reaction equation

HRID 1572878 reaction equation
[C:1]([CH3:2])(=[O:3])[C:4]1=[C:9]([CH3:10])[N:8]([c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][cH:16]2)[C:7](=[O:21])[CH:6]([C:22](=[O:23])[O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[CH:5]1[c:32]1[cH:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]1.[H:40][H:41].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[C:1]([CH3:2])(=[O:3])[C:4]1=[C:9]([CH3:10])[N:8]([c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][cH:16]2)[C:7](=[O:21])[CH:6]([C:22](=[O:23])[OH:24])[CH:5]1[c:32]1[cH:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 59666193Benzyl 5-acetyl-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyridine-3-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 596661955-Acetyl4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-c289f05f2e99451591debbf71eddb01a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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