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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1573376Generated: October 30, 2026

Trifluoroacetic acid → (4,4-Difluoro-piperidin-1-yl)-[1-(2-hydroxy-ethyl)-5-(1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-methanone

https://huagongshe.com/reaction/1573376

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant[1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-(1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanoneHCID 68423931—
Product(4,4-Difluoro-piperidin-1-yl)-[1-(2-hydroxy-ethyl)-5-(1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-methanoneHCID 16727146—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-e8bd86dfb7e1405ebae4880e9a29f469
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)