tert-butyl N-(1-oxopropan-2-yl)carbamate → N-Boc-2-amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene

HRID 1573382Notes

Reaction equation

HRID 1573382 reaction equation
[C:13](=[O:14])([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[NH:20][CH:21]([CH3:22])[CH:23]=[O:24].[CH3:1][C:2]1([CH3:11])[CH:3]([CH2:9][Br:10])[C:4]([CH3:7])([CH3:8])[CH2:5][CH2:6]1.[Mg:12]>>[CH3:1][C:2]1([CH3:11])[CH:3]([CH:9]=[CH:23][CH:21]([NH:20][C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH3:22])[C:4]([CH3:7])([CH3:8])[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 545705tert-butyl N-(1-oxopropan-2-yl)carbamateHCID 5462224MagnesiumHCID 136292612,2,5,5-Tetramethyl-1-cyclopentylmethylbromide

Product 1

HCID 70445522N-Boc-2-amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene

Sources & evidence

ORD record
ord-73fe31dd69b545c08227e405f82c23ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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