Toluene → N-cyclopropyl-1-{4-[(ethylamino)carbonyl]phenyl}-5-{3-[4-(trifluoromethoxy)phenoxy]propyl}-1H-1,2,3-triazole-4-carboxamide
Reaction equation
[CH2:13]([P:14]([CH2:15][CH2:16][CH2:17][CH3:18])[CH2:19][CH2:20][CH2:21][CH3:22])[CH2:23][CH2:24][CH3:25].[CH3:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[CH:26]1([NH:29][C:30](=[O:31])[c:32]2[n:33][n:34][n:35](-[c:41]3[cH:42][cH:43][c:44]([C:47](=[O:48])[NH:49][CH2:50][CH3:51])[cH:45][cH:46]3)[c:36]2[CH2:37][CH2:38][CH2:39][OH:40])[CH2:27][CH2:28]1.[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([OH:10])[cH:8][cH:9]1)([F:11])[F:12].[N:52]([C:53]([N:54]1[CH2:55][CH2:56][CH2:57][CH2:58][CH2:59]1)=[O:60])=[N:61][C:62]([N:63]1[CH2:64][CH2:65][CH2:66][CH2:67][CH2:68]1)=[O:69]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([O:10][CH2:39][CH2:38][CH2:37][c:36]2[c:32]([C:30]([NH:29][CH:26]3[CH2:27][CH2:28]3)=[O:31])[n:33][n:34][n:35]2-[c:41]2[cH:42][cH:43][c:44]([C:47](=[O:48])[NH:49][CH2:50][CH3:51])[cH:45][cH:46]2)[cH:8][cH:9]1)([F:11])[F:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5549094ffe96482e8f032896c9a01a5c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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