Chloride → 5'-Hydroxy-2'-iodo-4'-methoxyacetophenone

HRID 1573558Notes

Reaction equation

[Al+3:18].[Cl-:17].[Cl-:19].[Cl-:20].[Cl:21][CH2:22][Cl:23].[I:1][c:2]1[c:3]([C:14]([CH3:15])=[O:16])[cH:4][c:5]([O:10][CH:11]([CH3:12])[CH3:13])[c:6]([O:8][CH3:9])[cH:7]1>>[I:1][c:2]1[c:3]([C:14]([CH3:15])=[O:16])[cH:4][c:5]([OH:10])[c:6]([O:8][CH3:9])[cH:7]1

Participants

Reactant 4

HCID 312Chloride3×

HCID 6344Dichloromethane

HCID 104727Aluminum Cation

HCID 667611172'-Iodo-5'-isopropoxy-4'-methoxyacetophenone

Product 1

HCID 667608985'-Hydroxy-2'-iodo-4'-methoxyacetophenone

Sources & evidence

ORD record: ord-33e64f604945451bbecc77d8ede7276d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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