Potassium Cation → N-[2-amino-3-(3-chlorophenyl)propyl]-N-[4-(methoxymethyl)-5-([1,3]thiazolo[5,4-c]pyridin-2-yl)-1,3-thiazol-2-yl]acetamide

HRID 1573991Notes

Reaction equation

HRID 1573991 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH3:1][O:2][CH2:3][c:4]1[n:5][c:6]([NH:18][C:19]([CH3:20])=[O:21])[s:7][c:8]1-[c:9]1[s:10][c:11]2[cH:12][n:13][cH:14][cH:15][c:16]2[n:17]1.[Cl:28][c:29]1[cH:30][c:31]([CH2:32][CH:33]2[N:34]([S:36]([c:37]3[cH:38][cH:39][c:40]([N+:41]([O-:42])=[O:43])[cH:44][cH:45]3)(=[O:46])=[O:47])[CH2:35]2)[cH:48][cH:49][cH:50]1.[Cs+:26].[Cs+:27].[K+:51].[K+:52].[O-:53][C:54]([O-:55])=[O:56].[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[SH:57][CH2:58][CH2:59][OH:60]>>[CH3:1][O:2][CH2:3][c:4]1[n:5][c:6]([N:18]([C:19]([CH3:20])=[O:21])[CH2:35][CH:33]([CH2:32][c:31]2[cH:30][c:29]([Cl:28])[cH:50][cH:49][cH:48]2)[NH2:34])[s:7][c:8]1-[c:9]1[s:10][c:11]2[cH:12][n:13][cH:14][cH:15][c:16]2[n:17]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 15672-MercaptoethanolHCID 6228DimethylformamideHCID 19660Carbonate Ion2×HCID 104967Cesium cation2×HCID 57633920N-(4-(methoxymethyl)-5-(thiazolo[5,4-c]pyridin-2-yl)thiazol-2-yl)acetamideHCID 76571315(S)-2-(3-chlorobenzyl)-1-(4-nitrophenylsulfonyl)aziridine

Product 1

HCID 68993352N-[2-amino-3-(3-chlorophenyl)propyl]-N-[4-(methoxymethyl)-5-([1,3]thiazolo[5,4-c]pyridin-2-yl)-1,3-thiazol-2-yl]acetamide

Sources & evidence

ORD record
ord-900c2d040ce448dcaa95c680ebbf3930
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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