Sodium ion → 2-[4-(3-chloro-2-pyridinyl)-3,6-dihydro-2H-pyridin-1-yl]-N-(2,6-dimethylphenyl)acetamide

HRID 1574168Notes

Reaction equation

HRID 1574168 reaction equation
[CH3:14][c:15]1[c:16]([NH:22][C:23]([CH2:24][Cl:25])=[O:26])[c:17]([CH3:21])[cH:18][cH:19][cH:20]1.[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[Cl:1][c:2]1[c:3]([C:8]2=[CH:13][CH2:12][NH:11][CH2:10][CH2:9]2)[n:4][cH:5][cH:6][cH:7]1.[Na+:27].[Na+:28].[O-:29][C:30](=[O:31])[O-:32].[OH2:33]>>[Cl:1][c:2]1[c:3]([C:8]2=[CH:13][CH2:12][N:11]([CH2:24][C:23]([NH:22][c:16]3[c:15]([CH3:14])[cH:20][cH:19][cH:18][c:17]3[CH3:21])=[O:26])[CH2:10][CH2:9]2)[n:4][cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 707982-Chloro-N-(2,6-dimethylphenyl)acetamideHCID 688738073-Chloro-2-(1,2,3,6-tetrahydropyridin-4-yl)pyridine

Product 1

HCID 688742832-[4-(3-chloro-2-pyridinyl)-3,6-dihydro-2H-pyridin-1-yl]-N-(2,6-dimethylphenyl)acetamide

Sources & evidence

ORD record
ord-75322a8b0d97486d875721144b8aabed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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