Pyridine → 8-bromo-6-[(4-tert-butylphenyl)sulfonyl]-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[NH:7][CH2:8][c:9]1[c:10]([n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]1)[NH:11]2.[C:21]([CH3:22])([CH3:23])([CH3:24])[c:25]1[cH:26][cH:27][c:28]([S:31](=[O:32])(=[O:33])[Cl:34])[cH:29][cH:30]1.[CH3:41][N:42]([c:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1)[CH3:49].[Cl:50][CH2:51][Cl:52].[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[N:7]([S:31]([c:28]1[cH:27][cH:26][c:25]([C:21]([CH3:22])([CH3:23])[CH3:24])[cH:30][cH:29]1)(=[O:32])=[O:33])[CH2:8][c:9]1[c:10]([n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]1)[NH:11]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-31a7daacf99d4e7db7a82170aae7cdf6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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