Potassium Cation → 4-[4-Bromo-5-chloro-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester

HRID 1574304Notes

Reaction equation

HRID 1574304 reaction equation
[Br:1][c:2]1[c:3]([Cl:20])[cH:4][c:5]([OH:19])[c:6]([C:7](=[O:8])[N:9]([c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[CH3:17])[cH:18]1.[Br:27][CH2:28][CH2:29][CH2:30][C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37].[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[Br:1][c:2]1[c:3]([Cl:20])[cH:4][c:5]([O:19][CH2:28][CH2:29][CH2:30][C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[c:6]([C:7](=[O:8])[N:9]([c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[CH3:17])[cH:18]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 2757253tert-Butyl 4-bromobutanoateHCID 686026125-bromo-4-chloro-2-hydroxy-N-methyl-N-o-tolyl-benzamide

Product 1

HCID 686027224-[4-Bromo-5-chloro-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester

Sources & evidence

ORD record
ord-05de19230f34490883228078e18f52c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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