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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1574403Generated: November 1, 2026

Dimethyl Sulfoxide → 4-(5-(4-(3-Cyanopropyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-7-yl)-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1574403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantOxalyl chlorideHCID 65578—
Reactant4-(4-(7-(4-Cyano-3-(trifluoromethyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)phenyl)butanamideHCID 15951523—
Product4-(5-(4-(3-Cyanopropyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-7-yl)-2-(trifluoromethyl)benzonitrileHCID 15951627—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-931819dd1b26451b940100e46156ed8a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)