Dimethyl Sulfoxide → 4-(5-(4-(3-Cyanopropyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-7-yl)-2-(trifluoromethyl)benzonitrile
Reaction equation
[C:11](#[N:12])[c:13]1[c:14]([C:41]([F:42])([F:43])[F:44])[cH:15][c:16]([N:19]2[C:20](=[S:40])[N:21]([c:28]3[cH:29][cH:30][c:31]([CH2:34][CH2:35][CH2:36][C:37](=[O:38])[NH2:39])[cH:32][cH:33]3)[C:22]3([CH2:23][CH2:24][CH2:25]3)[C:26]2=[O:27])[cH:17][cH:18]1.[CH3:1][S:2]([CH3:3])=[O:4].[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[Cl:52][CH2:53][Cl:54].[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10]>>[C:11](#[N:12])[c:13]1[c:14]([C:41]([F:42])([F:43])[F:44])[cH:15][c:16]([N:19]2[C:20](=[S:40])[N:21]([c:28]3[cH:29][cH:30][c:31]([CH2:34][CH2:35][CH2:36][C:37]#[N:39])[cH:32][cH:33]3)[C:22]3([CH2:23][CH2:24][CH2:25]3)[C:26]2=[O:27])[cH:17][cH:18]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-931819dd1b26451b940100e46156ed8a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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