Trifluoroacetic acid → 5-(7-Methyl-4-morpholino-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

HRID 1574404Notes

Reaction equation

HRID 1574404 reaction equation
[F:38][C:39]([F:40])([F:41])[C:42]([OH:43])=[O:44].[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[n:9][c:10]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[c:11]3[c:12]([n:13]2)[c:14]([CH3:31])[c:15]([CH2:17][N:18]2[CH2:19][CH2:20][N:21]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:22][CH2:23]2)[s:16]3)[cH:6][n:7]1>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[n:9][c:10]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[c:11]3[c:12]([n:13]2)[c:14]([CH3:31])[c:15]([CH2:17][N:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]2)[s:16]3)[cH:6][n:7]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 56648672Tert-butyl 4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylate

Product 1

HCID 566486735-(7-Methyl-4-morpholino-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-ae721de4a2394dab9d676baa6b478ca9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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