Hydrochloric Acid → 1'-[(3-chloropyridin-2-yl)methyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

HRID 1574497Notes

Reaction equation

HRID 1574497 reaction equation
[Br:11][CH2:12][CH:13]1[CH2:14][CH2:15][CH2:16][CH2:17][O:18]1.[Cl:2][c:3]1[c:4]([CH2:9][Cl:10])[n:5][cH:6][cH:7][cH:8]1.[ClH:1].[NH:19]1[C:20](=[O:40])[C:21]2([CH2:22][O:23][c:24]3[cH:25][c:26]4[c:27]([cH:32][c:33]32)[O:28][CH2:29][CH2:30][O:31]4)[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]21>>[Cl:2][c:3]1[c:4]([CH2:9][N:19]2[C:20](=[O:40])[C:21]3([CH2:22][O:23][c:24]4[cH:25][c:26]5[c:27]([cH:32][c:33]43)[O:28][CH2:29][CH2:30][O:31]5)[c:34]3[cH:35][cH:36][cH:37][cH:38][c:39]32)[n:5][cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 1419172-(Bromomethyl)tetrahydro-2H-pyranHCID 145171573-Chloro-2-(chloromethyl)pyridineHCID 58224164Spiro[furo[2,3-g]-1,4-benzodioxin-8(7H),3'-[3H]indol]-2'(1'H)-one, 2,3-dihydro

Product 1

HCID 593522321'-[(3-chloropyridin-2-yl)methyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-11a3953219ea46cd8e9374415c1beba3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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