2,2,2-Trifluoroethanol → 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid

HRID 1574618Notes

Reaction equation

HRID 1574618 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1-[c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1.[F:18][C:19]([CH2:20][OH:21])([F:22])[F:23]>>[c:2]1([O:21][CH2:20][C:19]([F:18])([F:22])[F:23])[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1-[c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 866191836-Chloro-5-(4-chlorophenyl)-3-pyridinecarboxylic acid

Product 1

HCID 666869715-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid

Sources & evidence

ORD record
ord-d4396d4473ba4a0fa11f65f8838df1d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…