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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1574652Generated: October 31, 2026

Ammonium → 4-[2-(5-Bromo-2-fluoro-phenyl)-[1,3]dithian-2-yl]-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1574652

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantDiisopropylamideHCID 5062348—
Reactant2-(5-Bromo-2-fluorophenyl)-1,3-dithianeHCID 11403610—
Product4-[2-(5-Bromo-2-fluoro-phenyl)-[1,3]dithian-2-yl]-4-hydroxy-piperidine-1-carboxylic acid tert-butyl esterHCID 11306429—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-49ea5c3164764c5c9d261d6d79355ab1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)