Ammonium → 4-[2-(5-Bromo-2-fluoro-phenyl)-[1,3]dithian-2-yl]-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:14])[c:6]([CH:8]2[S:9][CH2:10][CH2:11][CH2:12][S:13]2)[cH:7]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:16][CH:17]([N-:18][CH:19]([CH3:20])[CH3:21])[CH3:22].[Cl-:37].[Li+:15].[NH4+:38].[O:23]=[C:24]1[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:14])[c:6]([C:8]2([C:24]3([OH:23])[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]3)[S:9][CH2:10][CH2:11][CH2:12][S:13]2)[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-49ea5c3164764c5c9d261d6d79355ab1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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