Ethanol → 1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine

HRID 1575010Notes

Reaction equation

HRID 1575010 reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH2:29]1[CH2:30][CH2:31][NH:32][CH2:33]1.[CH2:41]([OH:42])[CH3:43].[K+:38].[K+:39].[N:1]1([CH2:7][c:8]2[cH:9][cH:10][c:11]([C:14]#[C:15][CH2:16][CH2:17][O:18][S:19]([c:20]3[cH:21][cH:22][c:23]([CH3:24])[cH:25][cH:26]3)(=[O:27])=[O:28])[cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[OH2:40].[OH2:44]>>[N:1]1([CH2:7][c:8]2[cH:9][cH:10][c:11]([C:14]#[C:15][CH2:16][CH2:17][N:32]3[CH2:31][CH2:30][CH2:29][CH2:33]3)[cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 702EthanolHCID 813Potassium Cation2×HCID 962Water2×HCID 19660Carbonate IonHCID 31268PyrrolidineHCID 58981682HCID 58981682, compound

Product 1

HCID 101495161-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine

Sources & evidence

ORD record
ord-b4db44e98261413a838ba8b08b78755a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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