Pyridine → N-(4-Bromo-phenyl)-2-(2,2-difluoro-ethoxy)-6-methylamino-5-nitro-nicotinamide
Reaction equation
[Br:34][c:35]1[cH:36][cH:37][c:38]([NH2:39])[cH:40][cH:41]1.[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[Cl:1][C:2]([N:3]([CH3:4])[CH3:5])=[C:6]([CH3:7])[CH3:8].[Cl:42][CH2:43][Cl:44].[F:9][CH:10]([CH2:11][O:12][c:13]1[c:14]([C:15](=[O:16])[OH:17])[cH:18][c:19]([N+:24](=[O:25])[O-:26])[c:20]([NH:22][CH3:23])[n:21]1)[F:27].[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1>>[F:9][CH:10]([CH2:11][O:12][c:13]1[c:14]([C:15](=[O:17])[NH:39][c:38]2[cH:37][cH:36][c:35]([Br:34])[cH:41][cH:40]2)[cH:18][c:19]([N+:24](=[O:25])[O-:26])[c:20]([NH:22][CH3:23])[n:21]1)[F:27]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-81c5cab7109a44dd8dc0e8299872978f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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