Borane → Benzyl 2-(hydroxymethyl)-4-methoxypyrrolidine-1-carboxylate

HRID 1575413Notes

Reaction equation

HRID 1575413 reaction equation
[BH3:6].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][C:15](=[O:16])[N:17]1[CH:18]([C:24](=[O:25])[OH:26])[CH2:19][CH:20]([O:22][CH3:23])[CH2:21]1.[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1>>[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][C:15](=[O:16])[N:17]1[CH:18]([CH2:24][OH:25])[CH2:19][CH:20]([O:22][CH3:23])[CH2:21]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 128495191-[(Benzyloxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid

Product 1

HCID 20696664Benzyl 2-(hydroxymethyl)-4-methoxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-7161bafb89c24e4da6bf70a4049699a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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