1,3-Dibromopropane → 5-(3-bromo-propoxy)-2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-indole-1-carboxylic acid tert-butyl ester

HRID 1575608Notes

Reaction equation

HRID 1575608 reaction equation
[Br:39][CH2:40][CH2:41][CH2:42][Br:43].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](-[c:18]2[c:19]3[c:20]([n:21]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[n:22]2)[cH:30][cH:31][s:32]3)[cH:10][c:11]2[cH:12][c:13]([OH:17])[cH:14][cH:15][c:16]12.[C:33](=[O:34])([O-:35])[O-:36].[Cs+:37].[Cs+:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](-[c:18]2[c:19]3[c:20]([n:21]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[n:22]2)[cH:30][cH:31][s:32]3)[cH:10][c:11]2[cH:12][c:13]([O:17][CH2:42][CH2:41][CH2:40][Br:39])[cH:14][cH:15][c:16]12

Participants

5

Reactant 4

HCID 80011,3-DibromopropaneHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 576372832-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-hydroxy-indole-1-carboxylic acid tert-butyl ester

Product 1

HCID 576373315-(3-bromo-propoxy)-2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-indole-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-be4e640772ab423fa8053608e9277200
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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