2-Propenoic acid, 3-(3-methoxyphenyl)- → 3-(m-Methoxyphenyl)propionic acid

HRID 1576164Notes

Reaction equation

HRID 1576164 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[CH:12][CH:13]=1)[CH:6]=[CH:7][C:8]([OH:10])=[O:9].[H][H]>[Pd].C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:6][CH2:7][C:8]([OH:10])=[O:9])[CH:11]=[CH:12][CH:13]=1

Participants

5

Reactant 2

HCID 871552-Propenoic acid, 3-(3-methoxyphenyl)-HCID 178418361HCID 178418361, compound

Product 1

HCID 663363-(m-Methoxyphenyl)propionic acid

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ten grams of m-methoxycinnamic acid in 100 ml. of ethanol is hydrogenated with 0.5 g. of pre-reduced 10% palladium-on-charcoal until the uptake of hydrogen ceases. The catalyst is removed by filtration and the filtrate evaporated to yield 3-(m-methoxyphenyl)propionic acid.

Workup

  1. customThe catalyst is removed by filtration
  2. customthe filtrate evaporated

Sources & evidence

ORD record
ord-2359c906a8ad4bd9882f11726ce20b51
Source dataset
uspto-grants-1976_09
Patent number
US03979458

Reaction notes

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