HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → 5044-41-7
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | 2,5-Dimethoxytetrahydrofuran | HCID 79098 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5044-41-7 | HCID 820094 | — |
Reaction Steps
A 1-liter 3-neck flask equipped with stirrer, condenser, heating mantle, addition funnel and thermometer is charged with 47 g (0.5 mole) of 4-aminopyridine and 66 g (0.5 mole) of 2,5-dimethoxytetrahydrofuran. These materials are mixed together and 210 ml of glacial acetic acid is added dropwise with stirring over ten minutes while maintaining the temperature at less than 20°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03980089 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-b5e3202ffcfc4b8e83d6dbc7ed0e25a0 |
| Source note | uspto-grants-1976_09 |