反应详情

A solution of 3.5 g. of phenylsulfonyl chloride in 20 m. of anhydrous acetonitrile was added to a solution of 6.4 g. of 4-nitro-2,6-bis(trifluoromethyl)benzimidazole, sodium salt in 50 ml. of anhydrous acetonitrile. The mixture was stirred at room temperature for 2 hours, and the reaction mixture was filtered. The filtrate was evaporated to dryness under vacuum, and the residue was recrystallized from benzenepentane to yield 4-nitro-1-phenylsulfonyl-2,6-bis(trifluoromethyl)benzimidazole, m.p. 183°-185°C.

1. filtrationthe reaction mixture was filtered
2. customThe filtrate was evaporated to dryness under vacuum
3. customthe residue was recrystallized from benzenepentane