反应详情

A solution of 25.1 g. of 2,6-dinitro-4-trifluoromethylaniline in 100 ml. of pyridine was treated with trifluoroacetyl chloride, which has been prepared from 10 ml. of trifluoroacetic acid. Ethanol was added to the resulting mixture until it was homogeneous, and the reaction mixture was then evaporated under vacuum. The residue after evaporation was washed with water, dried, dissolved in acetone, and filtered. Chloroform was added to the filtrate until the product precipitated. The precipitate was separated by filtration and dried to obtain the purified intermediate, 2',6'-dinitro-4'-trifluoromethyl-2,2,2-trifluoroacetanilide.

1. customhas been prepared from 10 ml
2. customthe reaction mixture was then evaporated under vacuum
3. customThe residue after evaporation
4. washwas washed with water
5. customdried
6. dissolutiondissolved in acetone
7. filtrationfiltered
8. additionChloroform was added to the filtrate until the product
9. customprecipitated
10. customThe precipitate was separated by filtration
11. customdried