HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(4'-Fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 3-(4'-Fluoro-4-biphenylyl)-3-methyl-5-imino-pyrazolidine | HCID 178421589 | — |
| Product | 3-(4'-Fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one | HCID 21512675 | — |
Reaction Steps
26.9 g of 3-(4'-fluoro-4-biphenylyl)-3-methyl-5-imino-pyrazolidine [obtainable from 3-(4'-fluoro-4-biphenylyl)-2-butenoic acid nitrile and hydrazine] are boiled for 10 minutes with 150 ml of 20% strength aqueous hydrochloric acid and 150 ml of ethanol, and the solution is concentrated, neutralized and worked up in the usual manner to give 3-(4'-fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one, m.p. 194°-196°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03980795 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-a842ba4d04df46ed97d8ebdbfca79b96 |
| Source note | uspto-grants-1976_09 |