反应详情

26.9 g of 3-(4'-fluoro-4-biphenylyl)-3-methyl-5-imino-pyrazolidine [obtainable from 3-(4'-fluoro-4-biphenylyl)-2-butenoic acid nitrile and hydrazine] are boiled for 10 minutes with 150 ml of 20% strength aqueous hydrochloric acid and 150 ml of ethanol, and the solution is concentrated, neutralized and worked up in the usual manner to give 3-(4'-fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one, m.p. 194°-196°.

1. concentrationthe solution is concentrated