Ethanol → HCID 13289787, compound

HRID 1576562Notes

Reaction equation

HRID 1576562 reaction equation
[C:1]([CH:4]([CH2:16][CH3:17])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:15])[CH2:12][CH2:13][CH:14]=1)([OH:3])=[O:2].S(Cl)(Cl)=O.[CH2:22](O)[CH3:23]>>[C:1]([CH:4]([CH2:16][CH3:17])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:15])[CH2:12][CH2:13][CH:14]=1)([O:3][CH2:22][CH3:23])=[O:2]

Participants

4

Reactant 3

HCID 702EthanolHCID 24386Thionyl ChlorideHCID 217678162-(6-Carboxyoctyl)-2-cyclopentenone

Product 1

HCID 13289787HCID 13289787, compound

Procedure

Treatment of 2-(6-carboxyoctyl)-2-cyclopentone (Example 131) with thionyl chloride and then treatment of the acid chloride with ethanol in the manner described in Example 456 gives an amber oil. The oil is placed on a magnesia-silica gel column and eluted with 3:1 benzene:ether. The solvent is removed and the residue is distilled, b.p. 122°C. (0.06 mm).

Workup

  1. customgives an amber oil
  2. washeluted with 3:1 benzene
  3. customThe solvent is removed
  4. distillationthe residue is distilled

Sources & evidence

ORD record
ord-9282ce4a2e184f19b8d3adbde24cb7db
Source dataset
uspto-grants-1976_09
Patent number
US03981868

Reaction notes

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