Acetic Acid → HCID 54350597, compound

HRID 1576661Notes

Reaction equation

HRID 1576661 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH:11][C:12]2[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=2)[CH:9]=O)=[CH:4][CH:3]=1.[NH2:20][NH:21][C:22]([NH2:24])=[S:23].C(O)(=O)C.C([O-])(=O)C.[Na+]>CO>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH:11][C:12]2[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=2)[CH:9]=[N:20][NH:21][C:22]([NH2:24])=[S:23])=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 2723789ThiosemicarbazideHCID 54466296HCID 54466296, compound

Product 1

HCID 54350597HCID 54350597, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.0 g of 2-(4-bromophenyl)-3-(5-nitro-2-furyl) acrolein and 0.31 g of thiosemicarbazide are heated at reflux for 30 minutes in 25 cc of methanol with 0.3 g of glacial acetic acid and 1.0 g of sodium acetate. Upon cooling, the title compound is obtained as yellow brown crystals having a M.P. of 230°-237°.

Workup

  1. temperatureUpon cooling

Sources & evidence

ORD record
ord-4d7f4e03155a4c67927bf6c6c8d5a8a8
Source dataset
uspto-grants-1976_09
Patent number
US03982007

Reaction notes

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