HCID 53713602, compound → HCID 178513155, compound

HRID 1576662Notes

Reaction equation

HRID 1576662 reaction equation
C(=O)(O)O.[NH2:5][NH:6][C:7]([NH2:9])=[NH:8].[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([C:17](=[CH:20][C:21]2[S:22][C:23]([N+:26]([O-:28])=[O:27])=[CH:24][CH:25]=2)[CH:18]=O)=[CH:13][CH:12]=1>Cl.CO>[C:7]([NH:6][N:5]=[CH:18][C:17]([C:14]1[CH:15]=[CH:16][C:11]([Cl:10])=[CH:12][CH:13]=1)=[CH:20][C:21]1[S:22][C:23]([N+:26]([O-:28])=[O:27])=[CH:24][CH:25]=1)(=[NH:9])[NH2:8]

Participants

5

Reactant 2

HCID 53713602HCID 53713602, compoundHCID 178513185HCID 178513185, compound

Product 1

HCID 178513155HCID 178513155, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

A solution of 0.46 g of aminoguanidine hydrogen carbonate in 5 cc of 10% hydrochloric acid is added to 1.0 g of 2-(4-chlorophenyl)-3-(5-nitro-2-thienyl)acrolein in 20 cc of methanol, and the mixture is heated to 50° for one hour. Upon cooling, the hydrochloride of the title compound is obtained as yellow crystals having a M.P. of 225°-227°.

Workup

  1. temperaturethe mixture is heated to 50° for one hour
  2. temperatureUpon cooling

Sources & evidence

ORD record
ord-109b59e87d704c54a2515b0dca78044b
Source dataset
uspto-grants-1976_09
Patent number
US03982007

Reaction notes

Loading…