Isopropylamine → HCID 178432180, compound

HRID 1576672Notes

Reaction equation

HRID 1576672 reaction equation
[CH:1]([NH:4][CH2:5][CH:6]([OH:19])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-])=O)[C:10]=1[NH2:18])([CH3:3])[CH3:2].N[C:21]1C([N+]([O-])=O)=CC=C[C:22]=1OCC1OC1.C(N)(C)C.C(N)(C)(C)C>>[CH3:21][C:22]1[NH:18][C:10]2[C:9]([O:8][CH2:7][CH:6]([OH:19])[CH2:5][NH:4][CH:1]([CH3:3])[CH3:2])=[CH:14][CH:13]=[CH:12][C:11]=2[N:15]=1

Participants

5

Reactant 4

HCID 6363IsopropylamineHCID 6385Tert-ButylamineHCID 113448381-(2-Amino-3-nitrophenoxy)-2,3-epoxypropaneHCID 12484295HCID 12484295, compound

Product 1

HCID 178432180HCID 178432180, compound

Procedure

The 1-isopropylamino-2-hydroxy-3-(2-amino-3-nitrophenoxy)-propane (m.p. 108° - 110°C.) used as starting material can be obtained, in the manner described in Example 1, from 1-(2-amino-3-nitrophenoxy)-2,3-epoxy-propane, using 35 g. isopropylamine instead of 35 g. tert.-butylamine.

Workup

  1. customcan be obtained, in the manner

Sources & evidence

ORD record
ord-6f96e8f3a95348cab33eec9c6c973a37
Source dataset
uspto-grants-1976_09
Patent number
US03982012

Reaction notes

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