Succinimide → HCID 22764837, compound

HRID 1576738Notes

Reaction equation

HRID 1576738 reaction equation
[C:1]1([O:7][C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[K+].[C:13]1(=[O:19])[NH:17][C:16](=[O:18])[CH2:15][CH2:14]1>CCOCC>[O:7]([C:8]([N:17]1[C:13](=[O:19])[CH2:14][CH2:15][C:16]1=[O:18])=[O:9])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 11439SuccinimideHCID 14797Potassium HydroxideHCID 15891Phenyl chloroformate

Product 1

HCID 22764837HCID 22764837, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To 50 millimolses of phenylchloroformate in 25 ml of ether are added 16.7 ml of a 3M potassium hydroxide solution containing 50 millimoles of predissolved succinimide. The system is then stirred for about 1 hour, additional ether added and then restirred for about 1 hour. The insolubles formed are removed by filtering. Thereafter, the crude product is recrystallized from butanol saturated with water to give the desired product, melting point 132° - 133.5°C.

Workup

  1. stirringrestirred for about 1 hour
  2. customThe insolubles formed
  3. customare removed
  4. filtrationby filtering
  5. customThereafter, the crude product is recrystallized from butanol saturated with water

Sources & evidence

ORD record
ord-d4de682981ae4acebb8f04f81735ddec
Source dataset
uspto-grants-1976_09
Patent number
US03982891

Reaction notes

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