反应详情

温度

100 °C

To a mixture of 2-vinylquinoline (0.1 mole, 15g.) and glacial acetic acid (0.1 mole, 6 g.) in ethanol (95%, 100 ml.) N-phenylpiperazine (0.1 mole) was added and the solution was refluxed for 15 hrs. The solvent was removed and the remaining oil was heated in vacuo (1 mm. Hg) to 100°C. The oil left in the flask crystallized out on cooling and was recrystallized from ether-petroleum ether to give the titular product m.p. 79°C.

1. additionwas added
2. temperaturethe solution was refluxed for 15 hrs
3. customThe solvent was removed
4. waitThe oil left in the flask
5. customcrystallized out
6. temperatureon cooling
7. customwas recrystallized from ether-petroleum ether