HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 121291880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 86733287 | HCID 86733287 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 121291880 | HCID 121291880 | — |
Reaction Steps
Bromine (0.53 g.) in methanol (1.45 ml.) was added dropwise to a stirred solution of 3α-hydroxy-2β-ethoxy-5α-pregnane-11,20-dione (2.0 g) in methanol (15 ml) containing a trace of acetyl chloride at 0°. The addition took 2 hr. and the clear solution was then poured into water and collected by filtration, washed with water and dried in vacuo to give title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03983111 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-4c5d15c120164b69bcf0d05b361366ab |
| Source note | uspto-grants-1976_09 |