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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1576796Generated: October 25, 2026

Ethanolamine → alpha-[[(2-Hydroxyethyl)amino]methyl]benzyl alcohol

https://huagongshe.com/reaction/1576796

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantStyrene OxideHCID 7276—
SolventWaterHCID 962—
Productalpha-[[(2-Hydroxyethyl)amino]methyl]benzyl alcoholHCID 10727830.9%

Reaction Steps

Styrene oxide (1.2 g.), ethanolamine (0.6 g.) and water (0.05 g.) were heated at 70° with stirring for 24 hours. The mixture was cooled, evacuated and the oil formed triturated with ether to give title compound (550 mg.) m.p 93.5° - 95°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03983111
Source datasetuspto-grants-1976_09
ORD IDord-54578ca95f734989914b412731aed45e
Source noteuspto-grants-1976_09